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Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection. Lately, a great effort has been carried out to assay several drug candidates directed to viral targets direct-acting antivirals or against cellular targets host-targeting antivirals. Forum Users Search Support. Create a free account today! Forum statistics Total registered users:

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Zika virus associated with microcephaly. His work has contributed to the identification of key roles of cellular components and processes involved in flavivirus replication i. Along this line, anti-ZIKV activity has also been reported for hydroxycholesterol, which also regulates SREBP activity and is involved in the innate immune response to toll-like receptor ligands and interferon Adcock and coworkers 23 used a cell-based assay for the high-throughput screening of broad-spectrum antiviral compounds as ZIKV inhibitors.

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The Race To Find Antivirals for Zika Virus

Efficacy of the broad-spectrum antiviral compound BCX against Zika virus in cell culture and in a mouse model. Happy User Inactive Registered: Obatoclax, saliphenylhalamide and gemcitabine inhibit Zika virus infection in vitro and differentially affect cellular signaling, transcription and metabolism. You are not logged in. Curr Top Microbiol Immunol

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